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Lactimidomycin has a potent antiproliferative effect on tumor cell lines and selectively inhibit protein translation
with some localization of actin filament bundles at the cell boundaries
is a novel and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2
J Thorac Cardiovasc Surg
PT 1 Catalog No.:M23080-C Lactimidomycin has a potent antiproliferativePT 1 is a selective activator of AMPK with EC50 value of 0. 3 M for AMPK 111 . AMP activated protein kinase (AMPK) is serine threonine protein kinase that involved in cellular energy homeostasis and acts as an energy sensor. AMPK is a heterotrimer and increases ATP generation . PT 1 is a selective AMPK activator. PT1 activated human AMPK 1394, AMPK 2398 and AMPK(111) with EC50 values of 8, 12 and 0. 3 M, respectively. PT1 exhibited maximum activity
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