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EGFR-IN-1 14 mesylate 3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid

SKU: 249698543

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Description

3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum

CAS Number: 134-58-7

twice per day for 4 weeks) treatment can be delivered to mice in concentrations to sufficiently penetrate sMPNST tissue

InChiKey: FCEVNJIUIMLVML-QPSVUOIXSA-N

EGFR-IN-1 14 mesylate 3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoidEGFR IN 1 (compound 24) is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 1625677 63 5 Molecular Weight: 514. 58 Formula: C28H30N6O4 Chemical

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