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and subsequent enzymatic assays confirm the lack of activity against purified catalytic domains (IC50>>2 μM)
TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs)
Chemical Name: N-cyclopropyl-4-[6-(2
3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide
N-(4-Aminobenzenesulfonyl) Sulfamethoxazole-d4 Size:Contact [email protected] for quotation and subsequent enzymatic assays confirmProduct information CAS Number: 1346603 52 8 Molecular Weight: 412. 48 Formula: C16H16N4O5S2 Chemical Name: 4 (4 aminobenzenesulfonamido) N (5 methyl 1,2 oxazol 3 yl)(H)benzene 1 sulfonamide Smiles: [2H]C1=C(NS(=O)(=O)C2C=CC(N)=CC=2)C([2H])=C([2H])C(=C1[2H])S(=O)(=O)NC1C=C(C)ON=1 InChiKey: ULRBBWWPWOJYFE DOGSKSIHSA N InChi: InChI=1S C16H16N4O5S2 c1 11 10 16(18 25 11)20 27(23,24)15 8 4 13(5 9 15)19 26(21,22)14 6 2 12(17)3 7 14 h2
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