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nondepolarizing properties and lack of cardiovascular side effects
Intra-LC microinjection of orexin type-1 receptor antagonist SB-334867 attenuates the expression of glutamate-induced opiate withdrawal like signs during the active phase in rats
7 µM) and inducing HIF-1α and HIF-2α expression in mice
with low cytotoxicity (SI =2088)
Siramesine Hydrochloride Catalog No.:M8962-10 nondepolarizing properties and lack ofSiramesine, also known as Lu 28 179, is a potent sigma 2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress. Product information CAS Number: 224177 60 0 Molecular Weight: 491. 04 Formula: C30H32ClFN2O Synonym: Lu 28 179 hydrochloride
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