Bis-(N, N'-PEG4-NHS ester)-Cy5 lirioferine Degradation of cyclin-dependent kinase 4/6

Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods of use

InChi: InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9

Ormetoprim is a veterinary antimicrobial which commonly used in aquaculture and poultry industries

14(1):57-67

Bis-(N, N'-PEG4-NHS ester)-Cy5 lirioferine Degradation of cyclin-dependent kinase 4/6Bis (N,N' PEG4 NHS ester) Cy5 is an alkyl ether based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2107273 48 1 Molecular Weight: 1081. 64 Formula: C55H73ClN4O16 Chemical Name: 1 {15 [(2,5 dioxopyrrolidin 1 yl)oxy] 15 oxo 3,6,9,12 tetraoxapentadecan 1 yl} 2 [5 (1 {15 [(2,5 dioxopyrrolidin 1 yl)oxy] 15 oxo 3,6,9,12 tetraoxapentadecan 1 yl} 3,3 dimethyl 2,3 dihydro 1H indol 2 ylidene)penta 1,3 dien 1 yl]