![PD-089828 camsule.2Na Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M12225_1625548243.gif?v=1626938753)
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Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2
Ponatinib HCl
administration at 20 mg/kg is 20 and 15%
Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively
PD-089828 camsule.2Na Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2PD 089828 is an ATP competitive inhibitor of FGFR 1, PDGFR and EGFR (IC50s=0. 15, 1. 76, and 5. 47 M, respectively) and a noncompetitive inhibitor of c Src tyrosine kinase (IC50=0. 18 M). PD 089828 also inhibits MAPK with an IC50 of 7. 1 M. PD 089828 inhibits PDGF , EGF and bFGF mediated tyrosine kinase receptor autophosphorylation in vitro. PD 089828 has a long lasting cellular activity. Product information CAS Number: 179343 17 0 Molecular Weight: