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whereas cells that express mutant POLRMT (L796Q or L816Q) are resistant
InChiKey: IOEJYZSZYUROLN-UHFFFAOYSA-M
H3K9 and H3K36 methyl marks
7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide dihydrochloride
LP-922761 Size:Contact [email protected] for quotation whereas cells that express mutantLP 922761 is a potent, selective and orally active adapter protein 2 associated kinase 1 (AAK1) inhibitor with IC50s of 4. 8 nM and 7. 6 nM in enzyme and cell assays, respectively. LP 922761 also inhibits BMP 2 inducible protein kinase (BIKE) with an IC50 of 24 nM. LP 922761 exhibits no significant activity at cyclin G associated kinase (GAK), opioid, adrenergic 2 or GABAa receptors. Product information CAS Number: 1454808 95 7 Molecular Weight: 410.