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Effect of a novel squalene epoxidase inhibitor
LE135 is highly selective over RARγ
with EC50s of 30 nM and 100 nM for PPARγ1 and PPARγ2
As serine/threonine protein kinases which are involved in a number of biological processes
Retrorsine eltamivir (acid) Effect of a novel squaleneRetrorsine is a naturally occurring toxic pyrrolizidine alkaloid. Retrorsine can bind with DNA and inhibits the proliferative capacity of hepatocytes. Retrorsine can be used for the research of hepatocellular injury. Product information CAS Number: 480 54 6 Molecular Weight: 351. 39 Formula: C18H25NO6 Chemical Name: (1R,4Z,6R,7S,17R) 4 ethylidene 1,17 dihydrogenio 7 hydroxy 7 (hydroxymethyl) 6 methyl 2,9 dioxa 14 azatricyclo[9. 5. 1. 0,]heptadec 11
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