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MK-5046 - CAS# 1022152-70-0 sterol CA-5f is a potent late-stage

SKU: 25303588391

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Description

CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion

MK-5046 - CAS# 1022152-70-0 sterol CA-5f is a potent late-stageMK 5046 is a novel BRS 3 agonist, binds to BRS 3 with high affinity (mouse Ki = 1. 6 nM, human Ki = 25 nM). IC50 value: 1. 6 nM (Ki, for mouse), 25 nM (Ki, for human) Target: BRS 3in vitro: MK 5046 is a novel BRS 3 agonist, with improved BRS 3 potency, specificity, and pharmacokinetic properties that allows in depth investigation of BRS3 agonism in preclinical species and is also potentially suitable for use in humans. MK 5046 exhibits no appreciable

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