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Volasertib trihydrochloride - CAS# 946161-17-7 bradine Hydrochloride 11beta-Hydroxyprogesterone is a potent inhibitors

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Description

11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase

C6H8O7/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16

Midostaurin (PKC412) (25 mg/kg

N-[4-[2-methoxyethyl(methyl)amino]phenyl]-2-phenyl-5-(trifluoromethyl)-1

Volasertib trihydrochloride - CAS# 946161-17-7 bradine Hydrochloride 11beta-Hydroxyprogesterone is a potent inhibitorsVolasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP competitive Polo like kinase 1 (PLK1) inhibitor with an IC50 of 0. 87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models. Product information

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