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RP-64477 - CAS# 135239-65-5 9944 synthesis thereof and intermediates thereto

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Description

synthesis thereof and intermediates thereto

IL-6 and IFN-β expression in macrophages in vitro

Endothelin ET(B) receptor-mediated mechanisms involved in oleic acid-induced acute lung injury in mice

CAS Number: 474645-27-7

RP-64477 - CAS# 135239-65-5 9944 synthesis thereof and intermediates theretoRP 64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl coenzyme A: cholesterol O acyltransferase (ACAT). RP 64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo 2), hepatic (HepG2) and monocytic (THP 1) cell assays, respectively. Product information CAS Number: 135239 65 5 Molecular Weight: 498. 72 Formula: C29H42N2O3S Chemical Name: N' Butyl 4 (decyloxy) 4' (methylthio) N,3' bibenzamide

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