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InChiKey: RKUNBYITZUJHSG-FXUDXRNXSA-N
508(7495):215-21
Molecular Weight: 569
is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity
BMS-690514 Catalog No.:M10884-10 InChiKey: RKUNBYITZUJHSG-FXUDXRNXSA-NBMS 690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4, and vascular endothelial growth factor receptors (VEGFR) 1 3. BMS 690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo studies were conducted to characterize the pharmacokinetics and metabolism. Through integration of in vitro and in vivo pharmacokinetic data and antitumor efficacy in nude
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