PDE1-IN-3 omycin estolate Smiles: CC1(C)O[C@@H](OC2=CC=C3C(OC(=O)C(NC(=O)C4NC=C(C(=O)NC5C(=O)OC6=C(C=CC(O[C@@H]7OC(C)(C)[C@H](OC)[C@@H](OC(=O)C8=CC=C(C)N8)[C@H]7O)=C6C)C=5O)C=4C)=C3O)=C2C)[C@H](O)[C@H](OC(=O)C2=CC=C(C)N2)[C@H]1OC

Smiles: CC1(C)O[C@@H](OC2=CC=C3C(OC(=O)C(NC(=O)C4NC=C(C(=O)NC5C(=O)OC6=C(C=CC(O[C@@H]7OC(C)(C)[C@H](OC)[C@@H](OC(=O)C8=CC=C(C)N8)[C@H]7O)=C6C)C=5O)C=4C)=C3O)=C2C)[C@H](O)[C@H](OC(=O)C2=CC=C(C)N2)[C@H]1OC

10a-dihydrogenio-1

significantly increases the intracellular accumulation of epirubicin in Caco-2 cells and the absorption of epirubicin in rat small intestine

15-pentaoxaoctadecan-18-amido)propanamido]propanamido]-N-[4-(hydroxymethyl)phenyl]butanediamide

PDE1-IN-3 omycin estolate Smiles: CC1(C)O[C@@H](OC2=CC=C3C(OC(=O)C(NC(=O)C4NC=C(C(=O)NC5C(=O)OC6=C(C=CC(O[C@@H]7OC(C)(C)[C@H](OC)[C@@H](OC(=O)C8=CC=C(C)N8)[C@H]7O)=C6C)C=5O)C=4C)=C3O)=C2C)[C@H](O)[C@H](OC(=O)C2=CC=C(C)N2)[C@H]1OCPDE1 IN 3, compound 4 (WO2019156861), is a selective human phosphodiesterase 1 (PDE1) inhibitor. PDE1 IN 3 inhibits PDE4D and PDE6AB with IC50 values of 23. 99 M and 10 M, respectively. Product information CAS Number: 2370966 46 2 Molecular Weight: 312. 41 Formula: C18H24N4O Chemical Name: 3 {[1,1' bi(cyclopropane)] 1 yl} 7 (cyclobutylmethyl) 5,6 dimethyl 7H,8H [1,2,4]triazolo[4,3 a]pyrazin 8 one Smiles: CC1=C(C)N(CC2CCC2)C(=O)C2=NN=C(N12)C1(CC1)C1CC1