LY2157299 - TGFβ Inhibitor. CAS# 700874-72-2 size:10mg solid Schultz GS

Name: LY2157299 - TGFβ Inhibitor. CAS# 700874-72-2 size:10mg solid Schultz GS
Brand: pretereo.com
SKU: 21780543176
Price: 50.40 USD
Availability: InStock
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SKU: 21780543176

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Description

Schultz GS

ATP-competitive inhibitor of Akt

thus causes mitotic spindle defects

Bryan King

LY2157299 - TGFβ Inhibitor. CAS# 700874-72-2 size:10mg solid Schultz GSLY2157299, CAS No. 700874 72 2, is a novel potent and selective TGF receptor type I and type II (TRI II) inhibitor with IC50 of 86 nM and 2 nM, respectively. LY2157299 could inhibit the TGF induced Smad2 phosphorylation in HUVEC cells, promote VEGF induced HUVEC cell migration, and show dose dependent potentiation of VEGF or bFGF induced cell proliferation. It can also inhibit TGFmediated Smad2 activation and hematopoietic suppression in primary

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