dose-dependent exposure and modulation of the pharmacodynamic marker p-ERK is observed in the xenografts
It potently inhibits G9a/GLP methyltransferase activity in cells (IC50 ~10 nM in MCF7 cells)
Noscapine inhibits the viability of rat C6 glioma cells with an IC50 of 250 μM at 72 hours
Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder
Scutellarein tetramethyl ether Size:2mg solid dose-dependent exposure and modulation ofScutellarein tetramethyl ether (4',5,6,7 Tetramethoxyflavone) is a bioactive component of Siam weed extract. Scutellarein tetramethyl ether (4',5,6,7 Tetramethoxyflavone) exhibits anti inflammatory activity through NF B pathway. Scutellarein tetramethyl ether (4',5,6,7 Tetramethoxyflavone) modulats of bacterial drug resistance via efflux pump inhibition. Scutellarein tetramethyl ether (4',5,6,7 Tetramethoxyflavone) can enhance blood coagulation.