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PubMed PMID: 22485156
69(3):733-41
Formula: C67H125F3N34O17
CCN1C(=NC2=CN=C(C=C12)OC1=CC(=CC=C1)NC(=O)C1C=CC(=CC=1)OCCN1CCOCC1)C1=NON=C1N
ERK5-IN-2 Catalog No.:M21699-C PubMed PMID: 22485156ERK5 IN 2 is an orally active, sub micromolar, selective ERK5 inhibitor with IC50s of 0. 82 M, 3 M for ERK5 and ERK5 MEF2D, respectively. ERK5 IN 2 does not interact with the BRD4 bromodomain. ERK5 IN 2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis. Product information CAS Number: 1888305 96 1 Molecular Weight: 388. 19 Formula: C17H11BrFN3O2 Chemical Name: 4 (2 bromo 6 fluorobenzoyl)
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