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male BALB/c nude mice) treatment significantly delays tumor growth and decreases glucose metabolism
is a novel selective
Smiles: N#CC1=CC(=CC=C1OC1CCOCC1)C1=CC=NC(NC2C=CC(=CC=2)N2CCOCC2)=N1
CAS Number: 10030-85-0
RO2959 monohydrochloride Size:2mg solid male BALB/c nude mice) treatmentRO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1 Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL 2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. Product information CAS Number: 2309172 44 7
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