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Chemical Name: 2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1H-1
11 cells expressing BRD4(short)-FKBP12F36V with dTAG-13 leads to robust degradation of BRD4
InChi: InChI=1S/C10H14O3/c1-4-7-8(11)5-9(6(2)3)13-10(7)12/h5-6
AZD-2281 increases vascular perfusion in Calu-6 tumors established in a DWC model
7-Chloro-4-(piperazin-1-yl)quinoline 171 Chemical Name: 2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1H-17 Chloro 4 (piperazin 1 yl)quinolone is an important scaffold in medicinal chemistry. 7 Chloro 4 (piperazin 1 yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 M). 7 Chloro 4 (piperazin 1 yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1. 18 M and 0. 97 M, respectively. Product information CAS Number: 837 52 5 Molecular Weight: 247. 72 Formula: C13H14ClN3
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