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The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1
Formula: C17H40Cl3N7O4
Smiles: C[C@H]1COC(=O)N1C1=NOC2=C(F)C3=C(CC4([C@H]5[C@H](C)O[C@H](C)CN35)C(=O)NC(=O)NC4=O)C=C21
InChi: InChI=1S/C91H138N12O24/c1-60-18-12-11-13-19-61(2)76(112-8)55-70-24-21-66(7)91(111
Nemifitide diTFA adiol 17-(β-D-Glucuronide) (sodium salt) The histone deacetylase inhibitor MS-275Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide diTFA is a peptide analog of melanocyte inhibiting factor (MIF). Nemifitide diTFA can cross the blood brain barrier. Product information CAS Number: 204992 09 6 Molecular Weight: 922. 80 Formula: C37H45F7N10O10 Chemical Name: (2S) 2 {[(2S,4R) 1 [(2S) 2 amino 3 (4 fluorophenyl)propanoyl] 4 hydroxypyrrolidin 2
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