Zoliflodacin 8317 ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15

ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15

Monohydroxy Netupitant is the metabolite of Netupitant which is a potent and selective neurokinin-1 receptor (NK1) receptor antagonist

Acute (5 g/kg) and chronic (25 and 250 mg/kg) toxicology studies in uninfected mice show that

another group of rats treated with 600 μmol/kg of compound are allowed to recover for 14 days

Zoliflodacin 8317 ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15Zoliflodacin (ETX0914; AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram positive and Gram negative organisms, including S. aureus with the MIC90 of 0. 25 g mL. Product information CAS Number: 1620458 09 4 Molecular Weight: 487. 44 Formula: C22H22FN5O7 Chemical Name: (4'R,6'S,7'S) 17' fluoro 4',6' dimethyl 13' [(4S) 4 methyl 2 oxo 1,3 oxazolidin