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Smiles: CN1C=C(C2=C(C3=COC4=CC=CC=C34)C(=O)NC2=O)C2=CC(Br)=CC=C12
and high-affinity histamine H4 receptor antagonist
InChi: InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H
19)/b9-4+/i3+1D3
Enoximone Size:Contact [email protected] for quotation Smiles: CN1C=C(C2=C(C3=COC4=CC=CC=C34)C(=O)NC2=O)C2=CC(Br)=CC=C12Enoximone is an inotropic vasodilating agent and a selective and orally active phosphodiesterase III (PDE3) inhibitor with an IC50 of 5. 9 M. Enoximone induces vasodilatation and increases intracellular levels of cAMP by inhibiting cGMP inhibited PDE. Enoximone also exhibits PDE4 inhibitory effect with an IC50 of 21. 1 M for myocardial PDE4A. Enoximone has the potential for congestive heart failure research and has bronchodilatory, antiasthma and anti
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