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GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages
BAY-86-5258
2018 Jan 4
and trouble sleeping
JWG-071 hibitor GSK269962A suppressed IL-6 mRNA transcriptionJWG 071 is the first reported kinase selective chemical probe for ERK5. JWG 071 improves ERK5 activity and BRD4 selectivity. JWG 071 will be a much needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology. Product information CAS Number: 2250323 50 1 Molecular Weight: 612. 76 Formula: C34H44N8O3 Chemical Name: 2 (butan 2 yl) 5 ({2 methoxy 4 [4 (4 methylpiperazin 1 yl)piperidine 1 carbonyl]phenyl}amino) 9 methyl 2, 4, 6, 9 tetraazatricyclo[9.
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