TAK-733 0162 Although critical for in vitro

Although critical for in vitro binding

Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus

In cell-based assays

Formula: C23H16F3N3O6

TAK-733 0162 Although critical for in vitroTAK 733 is an orally bioavailable small molecule inhibitor of MEK1 and MEK2 (MEK1 2) with potential antineoplastic activity. MEK inhibitor TAK 733 selectively binds to and inhibits the activity of MEK1 2, preventing the activation of MEK1 2 dependent effector proteins and transcription factors, which may result in the inhibition of growth factor mediated cell signaling and tumor cell proliferation. MEK1 2 (MAP2K1 K2) are dual specificity threonine