TAK-700 R-form Catalog No.:M22571-C which reactivates tumor suppressor genes

which reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation

CC1=C(NS(=O)(=O)C2=CC=CC3C(=CC=CC=32)N(C)C)ON=C1C

RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways

InChiKey: TVJRDCQUZMGBAB-UHFFFAOYSA-N

TAK-700 R-form Catalog No.:M22571-C which reactivates tumor suppressor genesTAK 700 R form is a highly selective inhibitor of 17, 20 lyase with IC50 value of 38nM . TAK 700 is a potent and selective inhibitor of the 17, 20 lyase activity of CYP17A1 which is responsible for androgen biosynthesis. Thus, TAK 700 is selected as a candidate for treatment of prostate cancer through reducing the adrenal androgen production. As an inhibitor of CYP17A1, the selectivity of TAK 700 is important to avoid causing the drugdrug interactions