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CAS Number: 1414854-42-4
The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells
344940-63-2
03-10 µM) potently prevents the growth-inhibitory effects of TGF-β
MT-802 - CAS# 2231744-29-7 14616 CAS Number: 1414854-42-4MT 802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK) knockdown. MT 802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT 802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL). Product information CAS Number: 2231744 29 7 Molecular Weight: 787. 82 Formula: C41H41N9O8 Chemical Name: 2 [2 (2 {4 [4 amino 3 (4 phenoxyphenyl) 1H