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N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Fmk is an irreversible ribosomal

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Description

Fmk is an irreversible ribosomal S6 kinase inhibitor 1/2 inhibitor

It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body

C1CCC(C2=CC=CC=C21)C1NCCN=1

with Rho (Kd = 80 nM)

N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Fmk is an irreversible ribosomalN Acetyl calicheamicin, CAS No. 108212 76 6, is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1, 4 didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA,

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