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EPZ015666 was used at 5 µM final concentration in various in vitro assays
N-benzoylated phenoxazines and phenothiazines: synthesis
InChi: InChI=1S/C16H19N5O
2012 and by EMA on June 21
Retigabine 10067 EPZ015666 was used at 5Ezogabine, also known as Retigabine, is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment experienced adult patients. The drug was developed by Valeant Pharmaceuticals and GlaxoSmithKline. Ezogabine works primarily as a potassium channel openerthat is, by activating a certain family of voltage gated potassium channels in the brain. This mechanism of action is unique among antiepileptic drugs, and may hold promise
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