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TASIN-1 exhibited potent and selective toxicity toward DLD1 cells with IC50 value of 70 nM but not toward HCT116 cells (IC50 >50 μM)
Chemical Name: pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate
Smiles: CC(=O)OC1C=CC(CC(C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C)C2C=CC=CC=2)=CC=1
1 hour) pretreatment strongly inhibits NF-κB mediated genes (iNOS
MW-150 Catalog No.:M24962-C TASIN-1 exhibited potent and selectiveMW150 (MW01 18 150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38 MAPK with a Ki of 101 nM. MW 150 inhibits the ability of the endogenous p38 MAPK to phosphorylate an endogenous substrate MK2 in activated glia. Product information CAS Number: 1628502 91 9 Molecular Weight: 381. 47 Formula: C24H23N5 Chemical Name: 6 (4 methylpiperazin 1 yl) 3 (naphthalen 2 yl) 4 (pyridin 4 yl)pyridazine Smiles:
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