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After oral administration of TAS-102
E-7449 selectively binds to PARP 1 and 2
Armaiz-Pena GN
PubMed PMID: 10525088
U0126-EtOH - CAS# 1173097-76-1 174 After oral administration of TAS-102U0126 EtOH, CAS No. 1173097 76 1, is a highly selective inhibitor of MEK1 2 with IC50 of 0. 07 M 0. 06 M, 100 fold higher affinity for N3 S218E S222D MEK than PD98059. This inhibition of MEK1 2 is noncompetitive with ERK and ATP. Product information CAS Number: 1173097 76 1 Molecular Weight: 426. 56 Formula: C20H22N6OS2 Chemical Name: bis({amino[(2 aminophenyl)sulfanyl]methylidene})butanedinitrile; ethanol Smiles: CCO.
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