Ifosfamide - CAS# 3778-73-2 Size:Solid 2 mg InChi: InChI=1S/C20H13NO5/c22-20-12-5-10-2-4-15-19(26-9-24-15)18(10)17(13(12)7-21-20)11-1-3-14-16(6-11)25-8-23-14/h1-6H

InChi: InChI=1S/C20H13NO5/c22-20-12-5-10-2-4-15-19(26-9-24-15)18(10)17(13(12)7-21-20)11-1-3-14-16(6-11)25-8-23-14/h1-6H

PI3K pathway signaling is monitored through western blot analyses of Akt phosphorylation (a PI3K-mediated event)

Solubility: DMSO: 100 mg/mL(108

28)24-10-5-3-9(4-6-10)13(26

Ifosfamide - CAS# 3778-73-2 Size:Solid 2 mg InChi: InChI=1S/C20H13NO5/c22-20-12-5-10-2-4-15-19(26-9-24-15)18(10)17(13(12)7-21-20)11-1-3-14-16(6-11)25-8-23-14/h1-6HIfosfamide is a synthetic analogue of the nitrogen mustard cyclophosphamide with antineoplastic activity. Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Product information CAS Number: 3778 73 2