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PD173074 induces complete responses lasting >6 months in 50% of mice
(2016) Leukemia
2016 Jul 29
33)20-9-5-17(25)6-10-20/h5-15H
Diclofenac sodium (DSS) PD173074 induces complete responses lastingDiclofenac is a nonsteroidal anti inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX 1 and 2), thereby blocking the conversion of arachidonic acid to pro inflammatory proprostaglandins. This agent also may inhibit COX 2 mediated tumor angiogenesis. When inhibiting COX 2, Diclofenac may be effective in relieving
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