BMS 961 Size:Contact [email protected] for quotation Smiles: CC(O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(C)C(=O)NC(CCC(O)=O)C(=O)NCC(O)=O

Smiles: CC(O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(C)C(=O)NC(CCC(O)=O)C(=O)NCC(O)=O

InChi: InChI=1S/C23H26N6O2

and STAT3 and NFκB signaling in pancreatic cancer cells

CAS Number: 114-26-1

BMS 961 Size:Contact [email protected] for quotation Smiles: CC(O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(C)C(=O)NC(CCC(O)=O)C(=O)NCC(O)=OBMS961 is a potent and selective retinoic acid receptor gamma (RAR) agonist with IC50 values of 30 nM. RAR belongs to the family of nuclear receptors which regulates transcription. RAR mediates the anti proliferative and apoptotic effects of retinoids in cancer cells such as neuroblastoma cells. RAR is the principal receptor that regulates RA mediated growth arrest in keratinocytes. In vitro, application of BMS961on mouse ear skin was found to cause a