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BX471 is also able to displace 125I-MIP-1α/CCL3 binding to mouse CCR1 in a concentration-dependent manner with a Ki of 215±46 nM
deltarasin inhibits the interaction of RAS with PDEδ with KD of 41 nM
Sirtinol attenuates the proliferation and induces apoptosis of nonsmall cell lung cancer (NSCLC) H1299 cells and causes the significantly increased level of FoxO3a
3 nM (human Cdc25A)
Bis-PEG12-endo-BCN ltransferase BX471 is also able toBis PEG12 endo BCN is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information Molecular Weight: 941. 15 Formula: C48H80N2O16 Chemical Name: bis(bicyclo[6. 1. 0]non 4 yn 9 ylmethyl) (3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36 dodecaoxaoctatriacontane 1, 38 diyl)dicarbamate Smiles: O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1C2CCC#CCCC12)OCC1C2CCC#CCCC12 InChiKey: NJBQOQNHLPWBSB UHFFFAOYSA N InChi: InChI=1S
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