CC1(CC(=O)N2CCN(CC2)[C@@H]2C3=CC=CC=C3NC(=O)C3=CC=CC=C32)CCCC1)C(=O)NCCN1C(=O)N(C2C=CC=CC=2)N(C2C=CC=CC=2)C1=O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M26121_1635973254.gif?v=1635973255)
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Smiles: NC(N)=NCCC[C@H](NC(=O)CC1(CC(=O)N2CCN(CC2)[C@@H]2C3=CC=CC=C3NC(=O)C3=CC=CC=C32)CCCC1)C(=O)NCCN1C(=O)N(C2C=CC=CC=2)N(C2C=CC=CC=2)C1=O
Solubility: DMSO 50 mg/mL (200
1 or 5 μM of BVT948 for 24 h does not cause any significant changes in cell viability
Chemical Name: 3-fluoro-5-(2-methyl-1
NPD-1335 Catalog No.:M26121-C Smiles: NC(N)=NCCC[C@H](NC(=O)CC1(CC(=O)N2CCN(CC2)[C@@H]2C3=CC=CC=C3NC(=O)C3=CC=CC=C32)CCCC1)C(=O)NCCN1C(=O)N(C2C=CC=CC=2)N(C2C=CC=CC=2)C1=ONPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. Product information CAS Number: 2376326 31 5 Molecular Weight: 455. 55 Formula: C28H29N3O3 Chemical Name: 3 {5 [(4aS,8aR) 4 oxo 3 (propan 2 yl)
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