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TIC10 ehyde InChi: InChI=1S/C24H26N2O3/c1-23(2)9-10-24(3

SKU: 6482455862

4.4
USD80.00 USD115.00

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Description

InChi: InChI=1S/C24H26N2O3/c1-23(2)9-10-24(3

including lung

InChi: InChI=1S/C18H26ClN3

Anticancer Drugs

TIC10 ehyde InChi: InChI=1S/C24H26N2O3/c1-23(2)9-10-24(3ONC 201, also known as TIC10 and imipridone, is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53 independent manner and crosses the blood brain barrier. TIC10 induces a sustained up regulation of TRAIL in tumors and normal cells that may contribute to the demonstrable antitumor activity of TIC10. TIC10 inactivates kinases Akt and extracellular signal regulated kinase (ERK), leading to the translocation

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