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increases haemoglobin S (HbS) affinity for oxygen
Solubility: DMSO: 100 mg/mL(186
7'-(carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonate)
Van Rooyen DM
SGI-1776 oliquiritigenin increases haemoglobin S (HbS) affinitySGI 1776 is a small molecule pan Pim protein kinase inhibitor with potential antineoplastic activity. Pim kinase inhibitor SGI 1776 binds to and inhibits the activities of Pim 1, 2 and 3, serine threonine kinases, which may result in the interruption of the G1 S phase cell cycle transition, the expression of pro apoptotic Bcl2 proteins and tumor cell apoptosis. PIM kinases play key roles in cell cycle progression and apoptosis inhibition and may be