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349(2-3):237-43
Minegishi Y
Smiles: NC(=O)C1CC=CN(C=1)[C@@H]1O[C@H](COP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@H](OP(=O)(O[Na])O[Na])[C@@H]2O)N2C=NC3=C2N=CN=C3N)O[Na])O[Na])[C@@H](O)[C@H]1O
and thus topoisomerase II poisons will be less inhibitory in the K/VP
Phthalimide-PEG4-PDM-OTBS CT007093 349(2-3):237-43Phthalimide PEG4 PDM OTBS is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG4 PDM OTBS can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information Molecular Weight: 536. 73
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