ML281 Catalog No.:M7498-2 for 14 weeks) results in

for 14 weeks) results in a profound delay in tumor growth in NCR-Nu mice bearing MDA-MB-435/GFP tumor

which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis

2014 Mar 25

CAS Number: 1233948-35-0

ML281 Catalog No.:M7498-2 for 14 weeks) results inML281 is a potent and selective inhibitor of Serine threonine kinase 33 (STK33) with IC50 of 0. 014 M. ML281 is selectively toxic to KRAS dependent cancer cell lines. Product information CAS Number: 1404437 62 2 Molecular Weight: 389. 47 Formula: C22H19N3O2S Chemical Name: N [2 (3,4 Dihydro 3 oxo 2 quinoxalinyl) 4 (1 methylethyl)phenyl] 2 thiophenecarboxamide Smiles: CC(C)C1=CC(C2=NC3=CC=CC=C3NC2=O)=C(C=C1)NC(=O)C1=CC=CS1 InChiKey: HWOYIOLMBQSTQS