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8 nM in HEK293 cells)
InChi: InChI=1S/C21H23FN6O6S/c1-2-33-14-5-3-4-13(22)12(14)7-6-11-9-28(20-16(11)19(23)25-10-26-20)21-18(30)17(29)15(34-21)8-27-35(24
Adrenoceptors and dopamine receptors are not involved in the discriminative stimulus effect of the 5-HT1A receptor agonist flesinoxan
Molecular Weight: 587
SB-612111 hydrochloride Size:Contact [email protected] for quotation 8 nM in HEK293 cells)SB 612111 hydrochloride is a novel and potent human opiate receptor like orphan receptor (ORL 1) antagonist with a high affinity for hORL 1 (Ki=0. 33 nM). SB 612111 hydrochloride exhibits selectivity for , and receptors with Ki values of 57. 6 nM, 160. 5 nM and 2109 nM, respecticely. SB 612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin (HY P0183) in an acute pain model. Product information CAS Number: 371980 94 8
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