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Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2
8-trien-3-yl]formamido}-1-hydroxyethyl]phenoxy}-2-hydroxypropyl]-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4
c-Myc and Cyclin D1 are decreased and TCF/LEF transcriptional activation is notably down-regulated
CAS Number: 37079-84-8
TTA-A2 Catalog No.:M26158-C Atazanavir is a novel andTTA A2 is a potent, selective and orally active t type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA A2 is equally potent against the Cav3. 1 (a1G) and Cav3. 2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at 80 and 100 mV holding potentials. TTA A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy. Product information
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