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safe and effective HIV-1 attachment inhibitor
108 nmol/min/mg protein
The triphosphate is the fully activated metabolite that is toxic to the virus
Dipraglurant
Dipraglurant Catalog No.:M10339-2 safe and effective HIV-1 attachmentDipraglurant, aslo known as ADX 48621, is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa induced dyskinesia (PD LID). Blocking metabotropic glutamate receptor type 5 (mGluR5) has been proposed as a target for levodopa induced dyskinesias (LID) in Parkinson's disease (PD). Acute challenges of dipraglurant were efficacious on choreic and dystonic