ATN-161 trifluoroacetate salt Size:Solid 10 mg SNS-032 has low sensitivity to

SNS-032 has low sensitivity to CDK1 and CDK4 with IC50 of 480 nM and 925 nM

In high fat fed ApoE(-/-) mice

CLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9

CAS Number: 520-18-3

ATN-161 trifluoroacetate salt Size:Solid 10 mg SNS-032 has low sensitivity toATN 161 is a small peptide antagonist of integrin alpha5beta1 with potential antineoplastic activity. ATN 161 selectively binds to and blocks the receptor for integrin alpha5beta1, thereby preventing integrin alpha5beta1 binding. This receptor blockade may result in inhibition of endothelial cell cell interactions, endothelial cell matrix interactions, angiogenesis, and tumor progression. Integrin alpha5beta1 is expressed on endothelial cells and