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PF-3758309 dihydrochloride ergocristine mesylate Christensen JG

SKU: 74916591218

4.6
USD119.00 USD159.00

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Description

Christensen JG

InChi: InChI=1S/C32H32F3N3O2/c1-21-14-28-30(15-22(21)2)40-20-24(31(28)39)18-37(4)13-12-36(3)17-23-19-38(29-11-6-5-10-27(23)29)26-9-7-8-25(16-26)32(33

Smiles: [I-]

CAS Number: 298-93-1

PF-3758309 dihydrochloride ergocristine mesylate Christensen JGPF 3758309 dihydrochloride is a potent, orally available, and reversible ATP competitive inhibitor of PAK4 (Kd= 2. 7 nM; Ki=18. 7 nM). PF 3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. Product information Molecular Weight: 563. 55 Formula: C25H32Cl2N8OS Chemical Name: N [(1S) 2 (dimethylamino)

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