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TPX-0022 erophosphate disodium salt pentahydrate A review of its pharmacology

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Description

A review of its pharmacology

in LLc-PK-rDAT cell

Chemical Name: 4-fluoro-2-[(4R)-5

Chemical Name: 1-{[2-(2

TPX-0022 erophosphate disodium salt pentahydrate A review of its pharmacologyTPX 0022 (CSF1R IN 2) is a potent inhibitor of MET CSF1R SRC with enzymatic kinase inhibition IC50s of 0. 14 nM, 0. 71 nM and 0. 12 nM, respectively. TPX 0022 modulates the tumor immune microenvironment in preclinical models. Product information CAS Number: 2271119 26 5 Molecular Weight: 409. 42 Formula: C20H20FN7O2 Chemical Name: (11S) 16 amino 2 ethyl 6 fluoro 11 methyl 14 oxo 10 oxa 2,13,17,18,21 pentaazatetracyclo[13. 5. 2. 0,. 0,]docosa

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