Afuresertib HCl - CAS# 1047645-82-8 Catalog No.:M6857-2 PubMed PMID: 26970577

Name: Afuresertib HCl - CAS# 1047645-82-8 Catalog No.:M6857-2 PubMed PMID: 26970577
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Description

PubMed PMID: 26970577

Epub 2012 Mar 1

PubMed PMID: 26413751

InChiKey: ZZZQXCUPAJFVBN-UHFFFAOYSA-N

Afuresertib HCl - CAS# 1047645-82-8 Catalog No.:M6857-2 PubMed PMID: 26970577Afuresertib HCl, CAS No. 1047645 82 8, also known as GSK2110183, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is

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