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Nepicastat
Smiles: C/C(=N\NC1C(Cl)=CC(Cl)=CC=1Cl)/C1=CC(Cl)=CC=C1O
Solubility: Soluble in DMSO (15mg / mL)
18(15):4388-92
Crotonoside epram sodium salt NepicastatCrotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3 6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML. Product information CAS Number: 1818 71 9 Molecular Weight: 283. 24 Formula: C10H13N5O5 Chemical Name: 6 amino 9 [(2R,3R,4S,5R) 3,4 dihydroxy 5 (hydroxymethyl)oxolan 2 yl] 3,9 dihydro 2H purin 2 one Smiles: