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N-(4-acetamidophenyl)-Indomethacin amide Catalog No.:M22631-C Using the established scintillation proximity

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Description

Using the established scintillation proximity assay (SPA) assay

2-b]quinolin-1-yl)acetamide hydrochloride

Smiles: CN1C=C(N=C1C1CCN(CC1)C1N=CN=C2NN=CC2=1)C1=CC(=C(F)C=C1)C(F)(F)F

20 µM inhibits the cell growth of both cell lines effectively in a time- and dose-dependent manner

N-(4-acetamidophenyl)-Indomethacin amide Catalog No.:M22631-C Using the established scintillation proximityN (4 acetamidophenyl) Indomethacin amide is a reversible, potent and selective COX 2 inhibitor . Cyclooxygenase (COX) is an enzyme responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin. COX 1 is the constitutive isoform and is mainly responsible for the synthesis of cytoprotective prostaglandins in the gastrointestinal tract (GI) and of the proaggregatory thromboxane in blood platelets. COX 2 is

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