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Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements
InChiKey: DWVIOMKFHSRQQM-UHFFFAOYSA-N
65% and 55%
Pomalidomide4PEG3amine
TAK-875 er-5 Activation of EPAC1/2 is essentialTAK 875, is a potent, selective, and orally bioavailable GPR40 agonist, with a pharmacokinetic profile enabling long acting drug efficacy. TAK 875 showed potent plasma glucose lowering action and insulinotropic action during an oral glucose tolerance test in female Wistar fatty rats with impaired glucose tolerance. TAK 875 is currently in clinical trials for the treatment of type 2 diabetes mellitus. Product information CAS Number: 1000413 72 8
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