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CAS Number: 160003-66-7
F(dog)=44%]
6R)-2-{[(2S)-2-[(1S
TYP (50 mg/kg
ENMD-2076 ohesperidin dihydrochalcone CAS Number: 160003-66-7ENMD 2076 is an orally active, Aurora A angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD 2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over expressed in human cancers. ENMD 2076 also targets the VEGFR, Flt 3 and FGFR3 kinases which have been
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