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a feature especially relevant in a compound intended to treat mainly elderly patients
2(3):197-201
Nitisinone is a remarkable safe drug to use with few side effects reported
which demonstrates both potential opportunity and possible challenges to therapeutic agonism
Apilimod - CAS# 541550-19-0 ylic acid a feature especially relevant inApilimod, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL 23 production by the drug.
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